The ceremony included remarks by the United Nations Secretary-General, the President of the General Assembly, and the Permanent Representatives of Israel and the United States. Professor Debórah Dwork, the Holocaust scholar and educator, delivered the keynote address. Holocaust survivor Mr. Jacques Grishaver, and Dr. Ethel Brooks, the Romani scholar was speak. Dr. Karen Frostig was share her experience as the granddaughter of Holocaust victims. Musicians Ms. Shoshanna Shattenkirk, Professor Renee Jolles, and Mr. Michael Shaham (grandson of Holocaust survivors) was  perform. Cantor Nissim Saal was recite memorial prayers.

The United Nations Holocaust Memorial Ceremony marking the 2023 International Day of Commemoration in memory of the victims of the Holocaust is organized by the United Nations Department of Global Communications. The theme "Home and Belonging" highlights the humanity of the Holocaust victims and survivors, who had their homes and sense of belonging ripped from them by the perpetrators of the Holocaust. The violence of exclusion began with disinformation and hate speech that lent support to systemic injustice and discrimination, and marginalization and ended with genocidal killing. The theme reminds us of our responsibility to respond with humanity to the victims of atrocity crimes, to counter hate speech, antisemitism, Holocaust distortion and denial, and prejudice – to do all we can to prevent genocide.